TFE3 overexpression attenuates α-Syn toxicity in a mouse model of Parkinson's disease. TFE3 overexpression rescues autophagy defects of dop ...

Research led by York University's Faculty of Health reveals how a specific mutation in a protein called TRAF1 can shut down an overactive immune response, dramatically reducing inflammation in mice.

Research reveals how a specific mutation in a protein called TRAF1 can shut down an overactive immune response, dramatically reducing inflammation in mice. This discovery could pave the way for a new ...

Imagine a future where the grip of cocaine use disorder can be loosened, where cravings fade, and the risk of relapse ...

A recent study by Professor Junbo Ge team at Fudan University unveiled a novel mechanism by which intermittent fasting can ...

Researchers investigating the role of the protein CD44 in obesity and metabolic health found that CD44-deficient mice stayed lean even on a high-fat diet, while the control mice developed obesity. A ...

One particular challenge in the treatment of cancer is therapy resistance. An international research team has now discovered ...

Pannexin 1 (Panx1) is a high-conductance, voltage-sensitive ion channels that exhibit flexible gating behavior upon activation, enabling the passage of ions such as Ca2+, Na⁺, K⁺, and ATP. Panx1 is ...

For patients with stage III colon cancer participating in clinical trials, physical activity is associated with an att ...