The ligand Netrin mediates axon guidance through a combination of haptotaxis over short distances and chemotaxis over longer distances.

“These findings challenge a century of understanding about axon structure,” Shigeki Watanabe, study author and associate professor of cell biology and neuroscience at the Johns Hopkins ...

Biology is one of the most basic fields of science with direct application to humans. Our continued existence on planet Earth depends in large part on how we resolve problems of a biological nature.

Watanabe and his team used electron microscopy to examine unmyelinated axons in mice and determine whether the pearled pattern was the natural axon shape. Watanabe began his investigation by exploring ...

The Hodgkin-Huxley (H-H) theory of the action potential, formulated 50 years ago, remains one of the great success stories in biology ... range of data from squid axon, including the shape ...