The ligand Netrin mediates axon guidance through a combination of haptotaxis over short distances and chemotaxis over longer distances.

Watanabe and his team used electron microscopy to examine unmyelinated axons in mice and determine whether the pearled pattern was the natural axon shape. Watanabe began his investigation by exploring ...

“These findings challenge a century of understanding about axon structure,” Shigeki Watanabe, study author and associate professor of cell biology and neuroscience at the Johns Hopkins ...