Now, using a novel system developed at Janelia, researchers led by the Dudman Lab found that a part of the basal ganglia called the striatum is not involved in action selection as previously thought.

Structure-based drug design is the design and optimization of a chemical structure with the goal of identifying a compound suitable for clinical testing — a drug candidate. It is based on ...

They are divided into three portions: the outer ear, the middle ear, and the inner ear. Each has an intricate structure of bones, nerves, and muscles. Just like other parts of the body, the ears can ...

From a study that analyzed brain images of more than 2,500 people with Parkinson's disease in 20 different countries, scientists have been able to identify patterns of neurodegeneration and create ...

We noted many inefficiencies while discussing our past experiences working within traditional corporate structures. In researching a flat structure approach to building a business, we aimed to ...

together with its continuation to GPi/SNr has been termed the “hyperdirect” pathway because information flowing along this projection reaches the basal ganglia output structures with a shorter delay ...

These data provide novel insight into basal ganglia cognitive operations beyond movement and have implications for human striatal diseases and therapies targeting striatal pathways. A) We trained mice ...

Here, we review the functional role of one such structure, the basal ganglia. We examine research from animal electrophysiology, human neuroimaging, and behavior to consider characteristics of basal ...