A recent discovery has found a possible avenue to improve human health by better understanding how to engineer human stem ...

These intracellular signaling pathways, also called signal transduction cascades, typically amplify the message, producing multiple intracellular signals for every one receptor that is bound.

DNA damage response, or DDR for short, is the technical term for this. Specific signaling pathways usually initiate the ...

Volume electron microscopy reveals a novel cellular process that is critical for healthy brain development, with implications ...

The innate immune response is the body's first line of defense against infection, and a successful immune defense takes a ...

All of these technologies have in common the fact that they are single-ended, i.e. the signal is measured as a “high” or “low” level above ground. This is great for simple uses.

These sites bind to coreceptor CCR5 or CXCR4 on the membrane of the host cell (center panel), an event that initiates steps that culminate in the fusion of the HIV envelope with the host cell ...

Both Wnt and BMP signaling regulate maintenance of Lgr5+ intestinal stem cells, but their interplay remains incompletely ...

Endothelin is a peptide hormone known for its vasoconstrictive effects. Researchers at University of Tsukuba used ...

ACS membership includes access to Career Pathways, a program dedicated to helping budding chemists navigate their careers. There are four main career pathways available to chemical professionals: ...

Summary: Maraviroc is the first CCR5 coreceptor antagonist to receive marketing approval from the Food and Drug Administration (FDA) for the treatment of CCR5-tropic human immunodeficiency virus ...