Cytokine-induced killer cells are a heterogeneous cell population that can be expanded ex vivo from PBMC with the addition of IFN-γ, anti-CD3 antibody, and IL-2. In fact, many additional cytokines ...

Human NK cells are a subset of peripheral blood lymphocytes defined by the expression of CD56 or CD16 and the absence of the T-cell receptor CD3. NK cells comprise of 10–15% of the lymphocyte ...

Leveraging tumor organoids to model drug response in clear cell renal cell carcinoma. % Reactive Fragments 65.2 ± 26.8 43.0 ± 46.2 % CD56 + of TIL Expansion 14.1 ± 26.2 9.8 ± 4.6 % CD3 + of TIL ...

Blood and urine were routinely tested. CD4:CD8 ratios were determined and lymphocyte subsets were analyzed using CD3-, CD4-, CD8-, CD19- and CD56-reactive monoclonal antibodies and flow cytometry ...

Objectives NFIL3 is a key immunological transcription factor, with knockout mice studies identifying functional roles in multiple immune cell types. Despite the importance of NFIL3, little is known ...

Background Treatment strategies for Crohn’s disease (CD) suppress diverse inflammatory pathways but many patients remain ...

Hepatocellular carcinoma (HCC) remains an important complication of chronic liver disease, especially when cirrhosis occurs. Existing treatment strategies include surgery, loco-regional techniques, ...

These cells were stained with antibodies staining CD3, CD56 and other cell surface markers. After fixation and permeabilisation, these cells were stained with fluorochrome-conjugated antibodies ...

主要包括CD3+和CD56+细胞。 抗肿瘤活性 CIK细胞具有非MHC限制性的杀伤活性，能够识别并杀伤多种类型的肿瘤细胞，包括髓性白血病、黑色素瘤、肾细胞癌、非何杰金氏淋巴瘤等。其抗肿瘤作用主要通过直接细胞毒性和分泌多种细胞因子（如IFN-γ、TNF-α、IL-2等 ...

Panel D shows CAR detection on CD3+ lymphocytes on flow cytometric analysis ... intracellular antigen and negative for EBER, perforin, CD56, TdT, CD34, and CD1a, with a high Ki-67 proliferation ...

骨髓是人体造血的“工厂”，而骨髓增生异常肿瘤（MDS）则是这座工厂的“生产线故障”——血细胞发育异常，导致贫血、感染甚至白血病风险升高。 过去，MDS诊断高度依赖骨髓涂片的形态学观察，但仅凭细胞形态差异（如“病态造血”），难以区分MDS与其他良性血液病（如再生障碍性贫血）。2008年，欧洲白血病网络（ELN）首次将流式细胞术纳入MDS诊断体系，提出通过检测细胞表面抗原的异常表达模式（如CD34+祖 ...