1 Department of Cancer Biology, Vanderbilt University Medical Center, Nashville, Tennessee, USA 2 Department of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA 3 Division of ...

Diagnostic markers are biological parameters that aid the diagnosis of diseases. Examples include the presence of particular genetic variants and the levels of particular proteins in body fluids.

15 Deparaffinized 4-μm thick sections of ATs were incubated with antibodies directed against CD3 (Dako, Glostrup, Denmark) or F4/80 (Serotec, Raleigh, NC, USA). After washing, the slides were ...

It took decades, but in 2014, the first anti-CD3 BiAb, blinatumomab (Blincyto; Amgen, Inc.) was approved by the FDA for treatment of Philadelphia chromosome-negative relapsed or refractory precursor B ...

Biomarker testing looks for mutations, additions, deletions, or rearrangements in DNA. Biomarker testing can also help look for other key markers like levels of certain proteins or the amount of tumor ...

Freshly prepared peripheral blood mononuclear cells (PBMC) were treated with CD3×EpCAM BsAb, CD3 mAb, EpCAM mAb and control antibody at 150 ng/ml and incubated with or without target cells in 96-well ...