准确测量体内T细胞的增殖程度对于跟踪T细胞的动态反应至关重要。小鼠T细胞增殖可通过Ki67标记追踪。Ki67是一种支持染色体结构的核内蛋白，其表达量与细胞增殖的活跃相关，且在细胞周期的G1、S、G2、M期有表达，而在静止期（G0）几乎不表达。核酸染料 ...

Xiamen Cell Therapy Research Center, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen 361003, China ...

CD44 is a ubiquitous leukocyte adhesion molecule involved in cell-cell interaction, cell adhesion, migration, homing and differentiation. CD44 can mediate the interaction between leukemic stem cells ...

The innate immune system provides a crucial first line of defense against invading pathogens, and in addition, activates and guides subsequent adaptive immune responses. Although the role of innate ...

Immunophenotyping of T cell populations included the identification of naïve (CD3+CD44–CD62L+), memory (CD3+CD44+CD62L+), and effector (CD3+CD44+CD62L−) T cells [CD4+ and CD8+ naïve T cells ...

Ageing is associated with physical decline and the development of age-related diseases such as metabolic disorders and cancer. Few conditions are known that attenuate the adverse effects of ageing, ...