Inner Mongolia Key Laboratory of the Natural Products Chemistry and Functional Molecular Synthesis, College of Chemistry, and Materials Science, Inner Mongolia Minzu University, Tongliao 028000, China ...
Wnt5a signaling results in acyl protein thioesterase 1 (APT1) mediated depalmitoylation of pro-metastatic cell adhesion molecules CD44 and MCAM, resulting in increased melanoma invasion. The ...
This activity requires the intracellular domain and apparently the dimerization of the transmembrane chemokine ligand. Thus, shed soluble chemokines can generate auto- or paracrine signals by binding ...