A gene regulatory network is a set of genes, or parts of genes, that interact with each other to control a specific cell function. Gene regulatory networks are important in development ...

An inhaled gene therapy for cystic fibrosis developed by Boehringer Ingelheim is due to start clinical testing shortly, ...

We developed a new bispecific antibody, KVS-B043, which could recognize these pHLA complexes when the truncating mutations were in the TP53 gene and destroy cancer cells harboring such mutations ...

Collins, along with Matthew Lau ’25, developed the affordable CRISPRKit to make CRISPR gene-editing technology accessible to high school students underrepresented in the sciences. The kit was ...

Copyright 2025 The Associated Press. All Rights Reserved. Chicago Chess Records producer Gene Barge attends a screening of the film “Cadillac Records,” about ...

We applied a strategy of serial screening steps to 45 patients with congenital absence of the vas deferens and characterized cystic fibrosis transmembrane conductance regulator gene mutations in ...

Although newborn screening includes CF, this typically only covers a selection of common genetic variants, and with over 2000 reported in the cystic fibrosis transmembrane conductance regulator (CFTR) ...

The management of CF has been changing drastically over the last few years, especially after the introduction of CFTR modulators. Currently, 188,336 people have the disease in 96 countries, but only ...

Sionna’s portfolio is aimed at drugging the cystic fibrosis transmembrane conductance regulator (CFTR) protein, mutations in which are the main cause of the disease. Sionna’s drugs in development all ...

By introducing a gene from single-celled organisms into mouse cells, they generated stem cells capable of contributing to the development of a living mouse. The team led by Dr Alex de Mendoza of the ...

Dec. 4, 2024 — Researchers have uncovered a serious side effect of using the CRISPR-Cas gene scissors. A molecule designed to make the process more efficient destroys parts of the ...