Dec. 10, 2024 — In a single IV injection, a gene therapy targeting cBIN1 can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the ...

There are base layers for every situation, and without a few durable and dependable pairs of long johns, you might be left out in the cold. So I’ve tested a variety of layers, and list six of my ...

In this study, the authors developed a cell-based screening assay for the identification of small molecule inhibitors of nonsense-mediated decay (NMD). They used it to validate a novel small molecule ...

We developed a new bispecific antibody, KVS-B043, which could recognize these pHLA complexes when the truncating mutations were in the TP53 gene and destroy cancer cells harboring such mutations ...

Valentine’s Day celebrates partnerships—built on trust, balance, and mutual development. The same principles apply to Forex trading, where understanding the dynamics between currency pairs unlocks ...

Gené Teare is Crunchbase News' senior data editor. She conducts strategic research to explore and report on trends within private company data and focuses in particular on global venture funding ...

A study has identified a wheat nucleotide-binding and leucine-rich repeat (NLR) gene pair, RXL and Pm5e, that confers resistance to the devastating wheat powdery mildew disease. The study ...

The CRISPR/Cas9 gene editing technology uses a human engineered guide RNA to lead an enzyme called Cas9 to a specific region of DNA. Cas9 acts like a pair of “molecular scissors” and cuts the DNA.

Gene expression is the generation of a functional gene product from the information encoded by a gene, through the processes of transcription and translation. Gene products are often proteins ...

Approximately 5% of adult cancers depend on the gene PELO for survival, and disabling it can kill these cancer cells. These cancers have mutations in either the FOCAD or TTC37 genes.