The first CF rat model, CFTR tm1sage (termed CFTR-/- or KO), was designed in collaboration with SAGE (now Horizon Discovery) and subsequently characterized at UAB and distributed to the CF community.

The CFTR Protein Distribution Core offers high-quality, full-length recombinant cystic fibrosis transmembrane conductance regulator (CFTR) proteins expressed in and purified from mammalian cells. Wild ...

Sionna Therapeutics recently secured an initial public offering (IPO) of $191m on the Nasdaq stock exchange, signalling ...

The patient’s cells must produce the CFTR protein for the existing therapies to work ... they injected the lipid nanoparticles intravenously into a cystic fibrosis mouse model harboring the nonsense ...

In recent years, doctors have started using so-called CFTR modulator therapies to enhance the protein's function ... Scnn1b-transgenic mouse as an animal model for chronic obstructive pulmonary ...

In cystic fibrosis (CF), genetic mutations lead to faulty versions of CFTR, a protein key to moving ions in and out of cells. Improperly functioning CFTR leads to mucus buildup in the lungs of CF ...