AcrVIB1: The unexpected anti-CRISPR protein that tightens RNA binding
The CRISPR-Cas gene scissors offer a wide range of potential applications, from the treatment of genetic diseases to ...
Nature1 天
Biggest-ever AI biology model writes DNA on demand
An artificial-intelligence network trained on a vast trove of sequence data is a step towards designing completely new ...
AZoLifeSciences on MSN1 天
Novel Anti-CRISPR Protein Targets Cas13b RNA Nuclease
There are numerous potential uses for the CRISPR-Cas gene scissors, ranging from antiviral treatments and diagnostics to the ...
Nature7 天
The researchers on a quest to protect the gut from antibiotics
The crucial drugs can have unintended consequences. Innovative therapies could shield the microbiome from their effects.
The Scientist5 天
Exploring the World of Bacterial Genomes with Novel Sequencing Methods
Sequencing bacterial genomes allows scientists to study bacterial diversity, immunity, and the human microbiome, but it ...
诺奖得主Jennifer Doudna：CRISPR革命，能让基因变得更好吗？
2020年，詹妮弗·杜德纳（Jennifer A. Doudna）教授与埃马纽埃尔·夏彭蒂耶（Emmanuelle Charpentier）共同荣获诺贝尔化学奖，以表彰她们共同开发了基因组编辑方法CRISPR的卓越贡献。 受Frontiers for Young Minds邀请，杜德纳撰文解释了CRISPR的工作原理以及她与合作者是如何发现这一机制的。杜德纳说， ...
CRISPR system variant shows a novel DNA cleavage mechanism
Researchers have revealed new details about the CRISPR-Cas5-HNH/Cascade complex, a variant of the type I-E CRISPR-Cas system, ...
The EMBO Journal1 天
Refuse in order to resist: metabolic bottlenecks reduce antibiotic susceptibility
Most mutations that decreased antibiotic susceptibility were related to specific metabolic pathways. A MIC-increase to ...
New AI model could create 'app store for biology,' researchers say
The new doors AI and machine learning are opening to scientists undoubtedly will invite weighty ethical and moral questions ...
the-tartan3 天
NanoCas helps to unlock Mini-CRISPR, first march toward miniature gene editing
By Balambal Suryanarayanan CRISPR-Cas9 is a repurposed gene editing tool that allows scientists to cut, replace, and insert pieces of DNA in precise regions along the strand. Courtesy of NIH Image ...