However, when it comes to inserting exogenous DNA using homology-directed repair mechanisms, CRISPR editing can be woefully inefficient. Yet, inserting DNA is crucial to engineering CAR T cells.

When developing a drug, it’s important to understand its target and its mechanism of action. This is particularly crucial when repurposing an abandoned asset from another indication. CRISPR ...

As is typical, the research built on work going back years prior, specifically to 1987 when the first CRISPR mechanism was identified in E. coli, and their research in turn formed the foundation ...

CRISPR-Cas9 can elegantly and precisely cut away any desired region of DNA and has long been compared to a type of genetic ...

CRISPR/Cas9 Modifies Euglena to Create Potential ... 30, 2024 — Researchers have uncovered a surprising genetic mechanism that influences the vibrant and complex patterns on butterfly wings.

Researchers in Lithuania present the molecular structure of a new, more-versatile CRISPR system for gene editing.

CRISPR/Cas9 is a gene editing tool that has revolutionized biomedical research and led to the first FDA-approved CRISPR-based ...

CRISPR is a technology that can be used to edit genes and, as such, will likely change the world. The essence of CRISPR is simple: it’s a way of finding a specific bit of DNA inside a cell.

This study presents important findings on cold tolerance shared between hibernating and non-hibernating mammals, identifying a key molecule, GPX4, through multi-species genome-wide CRISPR screens. The ...

The CRISPR molecular scissors have the potential to revolutionize the treatment of genetic diseases. This is because they can be used to correct specific defective sections of the genome.