School of Pharmaceutical Sciences, Shanghai Jiao Tong University, Shanghai 200240, China ...

结果发现，与体外实验结果不同，R2lc 处理的小鼠前脑内 AhR、Cyp1b1 和 AhRR 基因表达降低，而 R2lcΔpks 处理组的基因表达情况和 PB-W1 处理组相似。这说明 R2lc 通过 pks 基因簇抑制了 AhR 通路基因的表达。 罗伊氏乳杆菌以菌株特异性方式调节紧密连接蛋白基因表达 ...

为解决结直肠癌（CRC）治疗耐药难题，研究人员开展铁死亡在 CRC 治疗中作用的研究。结果显示调节铁、氨基酸和脂质代谢诱导 CRC 铁死亡或成新策略。该研究为 CRC 治疗带来新希望，推荐科研读者阅读。 在全球范围内，结直肠癌（Colorectal ...

Birth control pills can result in hair loss as a side effect. However, this is usually temporary. As with any medication, the birth control pill can cause side effects. Some people may find that ...

George Coukos, MD, PhD, Department of Oncology, University Hospital of Lausanne, Rue du Bugnon 46, Lausanne 1011, Switzerland; e-mail: [email protected]. If you have the appropriate software installed ...

The dominant rationale to generate new (and to assess old) anticancer chemotherapeutic agents is to determine their cell-autonomous effects — that is, their capacity to reduce the growth ...

Background: Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune central nervous system (CNS) inflammatory and demyelinating disorder that can lead to serious disability and mortality.

Our previous findings that arachidonic acid-12/15-lipoxygenase (LOX)-generated metabolite 12(S)-HETE contributes to angiotensin II (AngII)-induced hypertension and 17β-estradiol protects from ...