1Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198-5900 USA 2Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...

In this Primer, Zhang et al. cover the physical and mathematical basis of UO-TDT and its application in various imaging platforms, and conclude with an outlook on how these techniques could be ...

Department of Vascular Surgery, The Dingli Clinical Institute of Wenzhou Medical University (Wenzhou Central Hospital), Wenzhou City, Zhejiang Province 325000, China Laboratory of Wenzhou Pan-Vascular ...

YOLO is a popular one-stage object detection model known for its speed and accuracy. It processes images in real-time, making it suitable for applications requiring quick detection. EfficientDet is ...

Mitochondrial DNA (mtDNA) is actively removed during spermatogenesis in a conserved process that enforces the uniparental ...

Applying this “turn-on” probe in live cells, we demonstrate an application not easily achieved by fluorescent reporter-based probes, detection of individual endogenous genomic loci using standard ...

The unsung heroes of flawless make-up routines, the best primers not only fix your make-up in place all day, they target all manner of skin concerns, too. Not layering a primer over moisturiser ...

Finding the right primer for dry skin is a challenge for us all – yes, including us beauty journos (hey 👋). If you're working with a flakey complexion, you'll know how annoying it is when ...

An artificial intelligence-powered weapon detection system failed to pick up the handgun a 17-year-old Nashville, Tennessee, student used in a school shooting Wednesday that killed a 16-year-old ...

BACKGROUND: Circular RNAs derived from both nuclear and mitochondrial genomes are identified in animal cells.

The pool of the long mutant oligos (up to 300 nt) can be used as DNA templates. These long oligos need to contain flanking wild-type sequences for primer binding, so they can be amplified and replace ...