Lebanese cannabis oil extract (COE) has been found to provide significant protection against kidney fibrosis caused by folic ...

The evidence for the authors' claims is convincing, combining state-of-the-art conditional gene deletion in the mouse lens with histological and molecular approaches. This work should be of great ...

Skeletal muscle tissue demonstrates global hypermethylation with aging. However, methylome changes across the time-course of ...

Famurewa, AC, Renu, K, Eladl, MA, Chakraborty, R, Myakala, H, El-Sherbiny, M, Elsherbini, DMA, Vellingiri, B, Madhyastha, H, ...

Elena Shagisultanova, MD, PhD, is working to uncover effective treatments for HER2-positive breast cancer patients by combining different drugs to counteract the cancer cells’ proliferation.

Dysregulated cell signaling underlies various diseases, emphasizing the importance of understanding these pathways for ...

A review discussing the therapeutic potentials of NK cell biology has been published in the journal Frontiers of Medicine.

Natural killer (NK) cells play an important role in the innate immune response to cancer and viral infections, and their ...

suggesting a role in NK cell exhaustion. TIPE2, a negative regulator of IL-15 signaling, is upregulated in various conditions and suppresses downstream AKT and Ral activation. The absence of TIPE2 ...

It involves cell proliferation, migration, differentiation ... it can exert neuroprotective effects through GPCR signaling pathways, including regulating the PI3K/Akt and ERK signaling pathways.

Studies have shown that PD inhibits the proliferation of liver cancer cells and induces apoptosis in tumor cells by suppressing Protein kinase B (Akt) phosphorylation (Jiang et al ... with 5-FU ...