Objective: The purpose of the present study was to demonstrate clinical equivalence between the application of collagenase ointment at 24- and 48-hour intervals in the healing of pressure ulcers.

In this randomized controlled trial, among patients with moderate Dupuytren’s contracture, collagenase injection was not ...

Oral informed consent was obtained from all patients. All patients were entered into an active run-in period with collagenase ointment (Iruxol® Mono, Laboratorios Knoll, SA, Madrid, Spain ...