该研究开发的CrisprAIE,是一种将CRISPR/Cas反应与“一到多”AIEgen发光荧光读取相结合的技术(图1)。这种“一到多”的AIEgen发光读出是通过使用AIEgen负载的双链DNA(dsDNA) reporters实现的,这些 ...
Recent research published in the journal “Science Bulletin” detailed the creation of a tool called ChCas12b that can ...
Feng Zhang, James and Patricia Poitras Professor in Neuroscience, MIT, to serve as Vice Chairman ...
Thanks to CRISPR, our medical specialists will soon have unprecedented control over how they treat and prevent some of our ...
In a paper published in Science Bulletin, a Chinese team of scientists conducted a GFP-activation assay screening 13 Cas12b ...
After lunch, Chase Beisel, Quanjiang Ji, Anna Cereseto, and Le Cong shared about novel CRISPR-Cas systems in the second session, including novel CRISPR-Cas12 systems and single-strand annealing ...
Thanks to CRISPR, our medical specialists will soon have unprecedented control over how they treat and prevent some of our most challenging genetic disorders and diseases. CRISPR (Clustered ...
CRISPR-Cas基因编辑技术在基础研究、动植物育种、核酸检测和基因治疗等多个领域展现出广泛的应用潜力。Cas蛋白作为该系统的核心组件,除了广为人知的II型Cas9蛋白外,V型Cas12家族(如Cas12a至Cas12n)也逐渐被发掘。尽管多种Cas12蛋白已被鉴定,但小型的Cas12蛋白 ...