A new discovery offers hope for Huntington’s disease. This discovery provides hope that a DNA repair process may help slow or ...
Research by UMass Chan Medical School scientists Sharon Cantor, Ph.D., and Jenna M. Whalen, Ph.D., poses a new explanation ...
Scientists are exploring gene editing as a way to correct trisomy at the cellular level. Using CRISPR-Cas9, researchers ...
Gene editing techniques may eventually allow trisomy to be treated at the cellular level, according to an in vitro ...
Building a gene editor took months. With CRISPR even high-schoolers can get hold of editing systems in the time it takes to ...
This tool is being used to correct typos in genes, including the huntingtin gene in HD (if you have a link to another HD CRISPR article). It can also be used to turn-off certain genes, which reduces ...
Both Tabrizi and Yang think that knocking down MSH3 could stave off HD pathology. Tabrizi noted that MSH3 also modifies other run-on repeats, including those causing fragile X syndrome, myotonic ...
1 CRISPR-Cas systems utilize RNA guides to direct Cas proteins to specific DNA sequences, where the Cas protein cleaves the DNA. This ability to precisely target and cut DNA is the foundation for ...