Evaluating colitis treatment efficacy and body composition changes using an IL-12/23 p40 neutralizing antibody, measured ...

To test our hypotheses, we designed a DSS- induced colitis model in C57BL/6 male mice. Apparent metrics were evaluated in each group of mice and performed histological analysis of relevant tissues.

Detailed methods regarding DSS colitis analysis, histological procedures and scoring, Swiss roll histology, immunohistochemistry, isolation of lamina propria (LP) lymphocytes, flow cytometry, BM ...

The aim of the present study was to clarify the role of ceramide–LMIR3 interaction in the development of IBD. Conclusions LMIR3-deficient colonic mast cells were pivotal in the exacerbation of ...

In recent studies using the Dextran Sulfate Sodium, DSS, colitis mouse model, PALI-2108 demonstrated a dose-dependent effect on key fibrotic pathways, underscoring its potential as an effective ...

Ulcerative proctitis (UP) is a form of ulcerative colitis (UC). Both are types of inflammatory bowel disease (IBD). But while proctitis affects only the rectum, ulcerative colitis can affect the ...

Language interfaces and extensions for an alternative implementation of EPRI's OpenDSS ...

Ulcerative colitis usually causes diarrhea, which may be watery and appear fluffy, mushy, or bloody. You may also experience constipation, which may present as small, hard stool lumps. Ulcerative ...

Positive updates across all programs, including updates from ongoing clinical studies and new translational data in preclinical models ...

Finding ulcerative colitis (UC) constipation relief can involve dietary strategies, increasing your fluid intake, biofeedback, medication, and even bowel training. You may find that you need to try ...