She initially received oral tretinoin (Vesanoid) followed by daunorubicin on days 1 through 3 and cytarabine on days 1 to 5 (planned treatment is to receive cytarabine for 2 more doses).
It has two candidates in phase 3 – lurbinectedin for small-cell lung cancer and JZP351 (liposomal daunorubicin and cytarabine) for acute myeloid leukaemia. The deal is also a first partnership ...
为解决多药 ABC 转运蛋白工作机制细节不明的问题,多国研究人员聚焦 BmrA 展开研究。发现 R6G 和 H?chst33342 可窄化 BmrA 构象范围,提升 ATP 利用效率。该成果有助于理解微生物耐药机制,推荐科研读者一读。
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