In addition to rod photoreceptor loss, many mutations in rod photoreceptor-specific genes cause degeneration of other neuronal types. Identifying mechanisms of cell–cell interactions initiated ...

Inherited retinal diseases (IRDs) are a group of monogenic disorders caused by mutations in more than 280 genes, and are characterized by progressive degeneration of photoreceptor cells in the retina.

In view of the oxygen-rich environment in the eye, it is particularly noteworthy that phospholipids containing docosahexaenoic acid (DHA), which are exquisitely sensitive to oxidative damage (1), are ...

This disrupts normal cell metabolism, leading to the death of photoreceptor cells and, eventually, geographic atrophy, which causes irreversible vision loss. Wet macular degeneration accounts for ...

More information: Guizhi Guo et al, Disruption of photoreceptor cilia is a critical event in the pathogenesis of retinal ...

However, the study provides limited new insights into the relationship between retinal lamination defects and overall retinal function. Neural lamination is a common feature of the central nervous ...

TOKYO -- Japanese researchers from Keio University and elsewhere announced Thursday that they have begun a clinical trial on a gene therapy to restore light sensitivity in patients with retinitis ...

"The results obtained show that the Ziapin2 molecule is extremely promising for restoring visual response in cases of photoreceptor degeneration," stated Fabio Benfenati, coordinator of the Center ...

16 the transplant operation involving photoreceptor cells derived from human induced pluripotent stem (iPS) cells. The female patient in her 60s was diagnosed with pigmentary degeneration of the ...