Tetrazine-PEG-SS-NHS作为一种可降解的ADC linker,是合成抗体偶联药物(ADC)的关键组件。ADC由抗体、linker和细胞毒素三部分组成,其中linker负责将抗体与细胞毒素连接起来,并在适当的时候释放毒素以杀死目标细胞。 工作机制:Tetrazine-PEG-SS-NHS中的二硫键在还原条件 ...
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ADCs can be divided into three chief components: the antibody, a linker, and a cytotoxic active ... specific to the cancer tissue subtype. If the ADC is transported to other body regions, there ...
mold is a faster drop-in replacement for existing Unix linkers. It is several times quicker than the LLVM lld linker, the second-fastest open-source linker, which I initially developed a few years ago ...
But that's good news, not for 'linkers', but for the fixed-income gilts that make up a majority of government IOUs. Say the government issues 6% gilts redeemable at 'par' usually £100 each in ten ...