Department of Pharmaceutics, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, 110016, China ...

Its effect is based on the breaking of the disulfide bridges of mucus glycoproteins ... With these two blocked thiol groups, erdosteine is an inactive prodrug. Erdosteine is stable only in ...

Beijing National Laboratory for Molecular Sciences, Radiochemistry and Radiation Chemistry Key Laboratory of Fundamental Science, College of Chemistry and Molecular Engineering, Peking University, ...

These organelles are of particular interest for the design and delivery of pH-dependent prodrugs and for devising strategies to inhibit degradation in these compartments. By choosing appropriate ...

Expert Rev Resp Med. 2007;1(3):307-316. Specific trials of erdosteine in geriatric subjects and in patients suffering from mild renal or hepatic failure did not show any impact on the rates of ...

Background: With poor treatment outcomes and prognosis, bladder cancer remains a focus for clinical research in the precision oncology era. However, the potential of disulfidptosis, a novel cell death ...

Table 1. Mechanisms of anti-septic efficacy of NMs. The anti-septic efficacy of NMs can be broadly categorized based on four key mechanisms. Firstly, NMs serve as highly efficient delivery systems for ...