If approved, Dupixent would be the first and only targeted medicine to treat BP in the U.S.; FDA decision expected by June 20, 2025Priority ...

The SARS-CoV-2 pandemic interrupted much respiratory research. Respiratory clinical academics joined colleagues in providing clinical care, and global research efforts were directed to finding new ...

Following acute myocardial infarction, eosinophil counts 5 to 7 days after onset are associated with risk of long-term mortality Eosinophil counts 5 to 7 days after onset in patients with acute ...

Results Allergic Tlr7 −/− mice displayed impaired IFN release upon RV1B infection, increased virus replication and exaggerated eosinophilic inflammation and airways hyper reactivity. Treatment with ...

eosinophils rapidly leave the bloodstream to enter tissues, mainly the gastrointestinal tract, lungs, adipose tissue, thymus, uterus, and mammary glands, where they regulate a variety of important ...

Methods and results: Mice were treated with chronic restraint stress. A double-labelling approach was taken to localise CRH expression in immune cells (including dendritic cells, mast cells, ...

Eosinophil-derived proteins including eosinophil secondary granule proteins (major ... We thank Shikha Sundaram, David Brumbaugh and Sean Colgan for their helpful comments on the manuscript ...

Previously, it has been suggested that type-2 innate immune cells, particularly eosinophils and their production of IL-4, play an essential role in effective muscle regeneration after acute injury. We ...

Business development is a critical function of any organization—small or larger enterprises. And over the years, one thing I've noticed is that businesses that are sustainable continually and ...

The authors recommend that EoE is diagnosed based on the presence of symptoms of esophageal dysfunction and at least 15 eosinophils per high-power field on esophageal biopsy. A systematic ...