Chemical biologists studying natural-product pathways encoded in genomes have unearthed new chemistry and insights into the evolution of biologically active metabolites. Chemical biology has ...
A variety of organisms, such as bacteria, fungi, and plants, produce secondary metabolites, also known as natural products. Natural products have been a prolific source and an inspiration for numerous ...
Department of Pharmaceutics, School of Pharmacy, Virginia Commonwealth University, Richmond, Virginia 23298, United States Departments of Ophthalmology, Pediatrics, Biomedical Engineering, and Massey ...
The results of this research lead to regulatory approval of nab-paclitaxel plus gemcitabine therapy, which is now a standard regimen for metastatic PC (87). Epothilones are a novel class of ...