Briola and co-authors determined the structure of the human CTF18 clamp loader bound to PCNA to high resolution, analyzed the structure, and tested a new mechanism involving a human-specific Ctf18 ...

This work will be of high interest to a broad swathe of scientists studying native macromolecules present at low concentrations in cells. Cryo-EM single-particle analyses typically require target ...

These details can reveal how molecular interactions ... allowing for clearer visualization of how different cellular ...

These details can reveal how molecular interactions contribute ... allowing for clearer visualization of how different cellular structures interact at the nanoscale—even in conventionally ...

The difference between a normal insulator and a topological insulator can be mathematically expressed by the topological number. For example ... can be extended to two-dimensional systems.