The systemic agent is the first approved by the FDA for patients with NSCLC or pancreatic adenocarcinoma harboring an NRG1 gene fusion.
Sites in Los Angeles and near San Francisco California are enrolling people with severe SCD for a trial to test a gene ...
U.S. Renal Care Enrolled First Patients in the VOICE Collaborative Clinical Trial of Vafseo® (vadadustat) for CKD Patients on Dialysis ...
HIBISCUS phase 2 data evaluating the safety profile and efficacy of etavopivat in adult and adolescent patients with sickle ...
The CRISPR-SCD trial is the first clinical attempt to use a non-viral delivery approach to directly correct the sickle cell ...
Investigators said patients experienced adverse effects in line with those expected for myeloablative conditioning with ...
Cyclosporin H boosts a new lentivirus-delivered gene therapy with enhanced anti-sickling properties in blood stem cells from ...
CRISPR is turned into a drug delivery system that helps recreate fetal hemoglobin, which then changes into red blood cells. Because the gene mutation for sickle cell disease is not found in fetal ...
Bilirubin, the byproduct of hemoprotein breakdown, particularly hemoglobin, is a critical marker ... a carbohydrate-restricted diet boosts β-cell function in type 2 diabetes, offering a ...
The literature supports that any increase in fetal hemoglobin is beneficial for patients with sickle cell disease. And most importantly, when sickle cell patients achieve fetal hemoglobin levels ...
Based on the initial data generated in the Phase 1b trial, we believe that pociredir has the potential to increase fetal hemoglobin to levels that could ameliorate symptoms of sickle cell disease.