CRISPR is turned into a drug delivery system that helps recreate fetal hemoglobin, which then changes into red blood cells. Because the gene mutation for sickle cell disease is not found in fetal ...
Bilirubin, the byproduct of hemoprotein breakdown, particularly hemoglobin, is a critical marker ... a carbohydrate-restricted diet boosts β-cell function in type 2 diabetes, offering a ...
The literature supports that any increase in fetal hemoglobin is beneficial for patients with sickle cell disease. And most importantly, when sickle cell patients achieve fetal hemoglobin levels ...
Based on the initial data generated in the Phase 1b trial, we believe that pociredir has the potential to increase fetal hemoglobin to levels that could ameliorate symptoms of sickle cell disease.