Circadian rhythms of macrophages are altered by conditions associated with the tumor microenvironment, including acidic pH. This may be responsible for the heterogeneity in circadian clock gene ...
These cells deal with microbes and repair tissue damage. Two main sub-types of immune cells are T cells and macrophages. T cells are designed to recognise the molecular signatures of particular ...
We have applied both conventional and conditional knockout mouse models of genes specifically involved in folate metabolism and transport (e.g., Folr1, Folr2, Folr4, Rfc1, Slc25a32, Mthfr and Pcft) to ...