Autophagy is a process by which cells break down and recycle their own components to maintain homeostasis. The research team scrutinized the autophagy process in astrocytes and discovered that ...
A research team has discovered a novel mechanism essential for initiating autophagy. The study highlights the role of ZDHHC13, an enzyme that palmitoylates ULK1, in triggering autophagy.
Monitoring autophagic flux is necessary for most autophagy studies. The autophagic flux assays currently available for mammalian cells are generally complicated and do not yield highly quantitative ...