The locus coeruleus was found to facilitate the transition between NREM and REM sleep states while maintaining an unconscious ...

In a study published Nov. 21 in the journal Nature Human Behaviour, researchers have uncovered significant genetic ...

In this paper, a CRISPR-based gene addition strategy at the CX3CR1 locus of human hematopoietic stem cells is proposed to efficiently generate microglia engineered for the regulated expression of ...

Depression, particularly in women, often co-occurs with reproductive health conditions like dysmenorrhea or painful menstrual ...

Depression may increase the risk of menstrual pain, or dysmenorrhea, through mechanisms such as sleep disturbances.

Oct. 28, 2024 — Using state-of-the-art technology, researchers have identified several specific steps needed for CRISPR to become active and perform its gene editing function. These preclinical ...

A new study uncovers the role of the brain's locus coeruleus (LC) in regulating sleep cycles, managing transitions between NREM and REM sleep. This brainstem region alternates between activity peaks ...

Gene regulation refers to the mechanisms that act to induce or repress the expression of a gene. These include structural and chemical changes to the genetic material, binding of proteins to ...

Genetic disorders are diseases caused by an abnormal gene, often described as a mutation. When such diseases are inherited (rather than the result of a random mutation), it means they are passed along ...

Nov. 25, 2024 — A groundbreaking method to profile gene activity in the living human brain has been developed. This innovative approach opens new avenues for understanding and treating ...