New therapies for managing aging could emerge from research into a new gene, which scientists have identified as a key driver ...

TFE3 overexpression attenuates α-Syn toxicity in a mouse model of Parkinson's disease. TFE3 overexpression rescues autophagy defects of dop ...

Background: Variable rates of HER2 protein overexpression and gene amplification have been reported in advanced ovarian cancers (AOC). Trastuzumab, tested only as a single agent, has been shown to ...

Northwestern Medicine scientists have discovered that inhibiting the GATA6 protein in mouse models of colon cancer reduced ...

Syros Pharmaceuticals, Inc. (NASDAQ:SYRS) (the “Company”) today announced that its Board of Directors (the “Board”) has approved and the Company inten ...

New therapies for managing aging could emerge from research into a new gene, which scientists have identified as a key driver ...

High dose and low dose of TSHA-102 continue to be generally well tolerated with no treatment-related SAEs or DLTs in all pediatric, adolescent ...

Gene therapy involves the introduction of new genes into cells, to restore or add gene expression, for the purpose of treating disease. Most commonly a mutated gene is replaced with DNA encoding a ...

Adult human hearts possess limited regenerative abilities, so losing cardiomyocytes (CMs) after injury can result in ...

This new review article highlights the crucial role of GATA6, a transcription factor, in pancreatic ductal adenocarcinoma ...