Germline gene therapy and somatic gene therapy are two quite different proposals, and the legitimate concerns and risks of the former should not be used to stall progress on the latter.

While these experiments might not be directed at any kind of actual therapy, perhaps they still represent, in some sense, a first step toward germ-line gene therapy to eradicate lethal genetic ...

Second, it represents only a baby step toward the ultimate goal — eliminating terrible lethal genetic diseases from families through germ-line gene therapy, which is discussed below. And finally ...

(Image: National Human Genome Research Institute) Germline gene therapy involves modifying the genes in reproductive cells (eggs or sperm) or early embryos. The introduced genetic changes are passed ...

However, it could also be done through egg or sperm cells (germline gene therapy), which is more controversial, as the inserted gene would pass down through the generations. While it could spare ...

Real-world data reveal ongoing gaps in clinical practice related to homologous recombination repair gene mutation (HRRm ...

Research in the field of human gene therapy is directed towards correcting genetic defects of somatic cells i.e., cells that do not contribute to the next generation. Human germ line therapy is ...

Resnik D B, Steinkraus H B and Langer P. J. Human Germline Gene Therapy: Scientific, Moral and Political Issues. RG Landes Bioscience, Austin , TX , 189 pages, 1999. Bock, J. H. and Langer, P. J.

most people saw gene therapy as simply a different kind of treatment for disease. However, debate continues about the ethical implications of changing germ-line cells (eggs or sperm), which would ...