腾讯网2 天
Nature | “分子剪刀”失控催生癌症“通用抗原”
引言在与癌症的博弈中，研究人员始终在追寻肿瘤细胞的致命弱点。传统T细胞疗法如同精密制导武器，通过识别癌细胞表面的突变抗原来发动攻击，却在实体瘤治疗中屡屡碰壁：肿瘤内部如同错综复杂的迷宫，不同区域的癌细胞携带迥异的基因突变（肿瘤异质性），而低突变负荷的 ...
Nature5 天
Peptides from abnormal RNA processing in cancer offer an immunotherapy target
Al Charest is in the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA. Read the paper: Tumour-wide RNA splicing aberrations ...