Acquired resistance to PD-L1 inhibition can rewire the interferon-regulated secretory machinery in tumor cells, altering the ...

*仅供医学专业人士阅读参考“日防夜防，家贼难防”，内鬼任何时候都让人头疼，当然也被恨得咬牙切齿，但又几乎是必然存在的。在抗癌这条战线上，都不说免疫细胞整体纯纯的某黑衣酒厂了，就算是限定到T细胞乃至CD8+T细胞，那肯定也有给抗癌战友拖后腿的家伙，得早 ...

CD8-positive T cells are a critical subpopulation of MHC class I-restricted T cell and are mediators of adaptive immunity. They include cytotoxic T cells, which are important for killing cancerous ...

Cytotoxic T cells are CD8-postive T cells that are specialized for the direct killing of cells that are infected (particularly with viruses), cancerous or damaged in other ways. They express the ...

GSEApy is a Python/Rust implementation for GSEA and wrapper for Enrichr. GSEApy can be used for RNA-seq, ChIP-seq, Microarray data. It can be used for convenient GO enrichment and to produce ...

For in vivo GPX4 deletion, TAM was prepared and administrated as previously described (17). For in vitro GPX4 deletion, enriched CD8 + T cells from Gpx4 fl/fl-ERT2Cre-P14 mice were treated with 5 μM 4 ...

The neurotrophic factor Neuritin can moderate T-cell tolerance and immunity through both regulatory T (Treg) and effector T cells, promoting Treg cell expansion and suppression while dampening ...

“It shows that the ability to learn from spaced repetition isn’t unique to brain cells, but, in fact, might be a fundamental property of all cells.” Not only does this research on non-brain cells ...

(C) Log2 fold-change of the inflammatory signaling pathway activity between endometriosis patients – E, and controls – C in the different cell-types defined in Shih. et al. Horizontal bars show ...

You can increase white blood cells (WBCs) by taking certain medications and eating immune-boosting foods, like yogurt, lean protein foods, antioxidant-rich vegetables, and more. Maintaining a normal ...

Tesla’s top battery cell supplier, CATL, is throwing some cold water on Tesla’s battery plans and the CEO even said that Elon Musk “doesn’t know how to make battery cells.” Contemporary ...

1 knocked down human THP-1 cells was linked to genes overexpressed in URE Δ mice. To this end, we filtered for all RUNX1 peaks within ±50 kb windows of the signature 1–4 transcription start sites (TSS ...