Why does the COVID-19 virus make some people sicker than others? For years, scientists have looked to a critical piece of ...

For years, scientists have looked to a critical piece of immune system machinery - known as the interferon pathway - for answers. There, when our cells sense an infection, they release a protein known ...

Researchers have discovered a protein variant that serves as a knob for regulating the body's innate immune response. The findings could lead to new therapies for Long COVID, autoimmune disorders, and ...

Why does the COVID-19 virus make some people sicker than others? For years, scientists have looked to a critical piece of ...

Aligos Therapeutics focuses on ALG-000184 for CHB and ALG-055009 for MASH, targeting large, underserved markets with growing ...

Kymera Therapeutics is a biotech company with promising candidates in its pipeline for inflammatory disorders. Read why KYMR ...

Cancer cells impair monocyte-mediated T-cell activation by disrupting inflammatory pathways in the tumor microenvironment.

Prostate cancer and other cancers characterized by “cold” tumors could become more responsive to checkpoint blockade if UBA1 is inhibited.

Investigators from the Mass General Brigham healthcare system will present research discoveries and outcomes from clinical trials at the 2024 American Society of Hematology (ASH) Annual Meeting, held ...

including the entry proteins ACE2 and transmembrane serine protease 2 (TMPRSS2); 21 proteins in the interferon-I (IFN-I) antiviral response pathway; and tethrin, a protein that suppresses new virion ...

Methods: We evaluated the expression of AMPK signaling pathway components and contractile vascular smooth muscle cell (VSMC)-related genes in AAA samples from mice using reverse ...

However, its precise pathogenesis remains elusive. Consequently, researchers are dedicated to uncovering CI-AKI’s pathophysiology and signaling pathways, including inflammation, oxidative stress, ...