"Intriguingly, under normal oxygen levels in the body, called normoxia, IFN-g induction and glycolysis in T cells are not mediated by HIF1α, a primary regulator of glycolysis, but by its widely ...

The regulator HIF1α functions in a cancer-microenvironment that lacks oxygen, and it may be involved in resistance to immune ...

For years, scientists have looked to a critical piece of immune system machinery - known as the interferon pathway - for answers. There, when our cells sense an infection, they release a protein known ...

Researchers have discovered a protein variant that serves as a knob for regulating the body's innate immune response. The findings could lead to new therapies for Long COVID, autoimmune disorders, and ...

Researchers have shown how genetic defects in Toxoplasma gondii are rescued if co-infected with normal parasites, thanks to supportive secreted proteins.