Immune checkpoint blockades, or ICBs, have revolutionized treatment for various advanced cancers. However, their ...
The regulator HIF1α functions in a cancer-microenvironment that lacks oxygen, and it may be involved in resistance to immune ...
including the entry proteins ACE2 and transmembrane serine protease 2 (TMPRSS2); 21 proteins in the interferon-I (IFN-I) antiviral response pathway; and tethrin, a protein that suppresses new virion ...
Researchers Develop Promising Therapy Treatment That Can Kill Glioblastoma Cells in Newly Discovered Brain Pathway Aug. 2, 2024 — A new pathway that is used by cancer cells to infiltrate the ...
Prostate cancer and other cancers characterized by “cold” tumors could become more responsive to checkpoint blockade if UBA1 is inhibited.
1 Department of Molecular Cell Biology, VU Medical Centre/VU University Amsterdam, 1081 BT Amsterdam, The Netherlands 2 Division of Clinical Immunology and Rheumatology, Academic Medical ...
In an interview, Vincent Law, of Moffitt Cancer Center, discussed a new study that offers hope for patients with melanoma ...