By knocking out the gene for the protein IGFBP7, the researchers discovered that insulin secretion improved. Reduced insulin secretion leads to elevated blood glucose levels and an increased risk ...

日本东京大学等机构的研究人员通过动物实验发现，实验鼠心脏中老化的血管内皮细胞会分泌蛋白质IGFBP7，而这种蛋白质会抑制心肌细胞的线粒体 ...

Senescent cells secrete various proteins involved in cellular aging and pathological processes, including the metabolic protein insulin-like growth factor-binding protein-7 (IGFBP7). Using proteomics, ...