In the current study, we sought to determine the role of survivin in the apoptosis resistance of primary fibroblasts isolated from the lungs of patients with Idiopathic Pulmonary Fibrosis (IPF), a ...

Comprehensive Pneumology Center, Institute of Lung Biology and Disease (iLBD), Ludwig-Maximilians-University and Helmholtz Zentrum München, Neuherberg/Munich, Germany Background: Idiopathic pulmonary ...

Idiopathic pulmonary fibrosis (IPF) is a fatal disease that's all the more difficult for patients because of a lack of awareness and investment in supporting people with the condition. In the week ...

In part 2 of our interview, Cesar Davila-Chapa, MD, discusses key findings, limitations, and future research directions from his study on racial disparities in idiopathic pulmonary fibrosis (IPF ...

This important study describes a first-in-human trial of autologous p63+ stem cells in patients with idiopathic pulmonary fibrosis, a lethal condition for which effective treatments are lacking. The ...

Development of therapies that halt or reverse IPF and PAH progression is a significant unmet need. Improved diagnostic tools are essential for earlier detection and intervention in IPF and PAH.

Key Highlights: Enhanced iNKT activity correlates with progression of fibrosis in MASH patients and key proinflammatory genes in BAL from IPF patients ... of pro-fibrotic fibroblasts; Inhibits ...

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Fibroblasts are specialized cells in connective tissues that play an important role in wound healing and tissue repair. They produce and organize the so-called extracellular matrix, a network of ...

Skin fibroblasts and endothelial cells treated with CCL24 or SSc serum with or without ... There are major similarities in the features of the lung disease in patients with SSc and IPF. In both ...