Objective To study the role of α4β7 integrin for gut homing of monocytes and to explore the biological consequences of therapeutic α4β7 inhibition with regard to intestinal wound healing. Design We ...

A substantial and persuasive body of data now exists that supports the view that integrin alpha V beta 3 plays a critical part in activated macrophage dependent inflammation, osteoclast development, ...

Table 1 Potential actions of macrophage migration inhibitory factor ... binding to leukocyte-expressed receptors and inducing leukocyte integrin activation and subsequent leukocyte adhesion.

Dr. McCormick’s current research focuses on cutaneous immune regulation and innate immunity. His laboratory group addresses the mechanisms of immune regulation in psoriasis. Understanding the function ...

Dr. McCormick’s current research focuses on cutaneous immune regulation and innate immunity. His laboratory group addresses the mechanisms of immune regulation in psoriasis. Understanding the function ...