The insulin cells are killed by an autoimmune process in type 1 diabetes, which affects roughly nine million people worldwide. Although islet transplantation is a promising approach for treating ...

Three people with type 1 diabetes who received Vertex Pharma’s islet cell therapy VX-880 have been able to come off insulin altogether within a year, raising the prospect of a life without ...

The pancreatic islet is the only human tissue that produces insulin in response to rising blood glucose levels. In type 1 diabetes, the immune system attacks and slowly destroys these islets ...

In a recent analysis of 1210 participants from the Collaborative Islet Transplant Registry, primary graft function, measured 1 month after transplantation, was the main predictor of 5-year success of ...

Adding engineered human blood vessel-forming cells to islet transplants boosted the survival of the insulin-producing cells and reversed diabetes in a preclinical ...

Researchers have developed a method using engineered blood vessel cells (R-VECs) to improve islet transplantation which could offer a safer and more effective treatment for type 1 diabetes. In a study ...

You will be redirected to our submission process. The restoration of glycemic control through islet transplantation currently remains as one of the only approaches to achieve insulin independence for ...

Zebrafish provide a useful platform for drug discovery in NDD that is time- and cost-efficient (Figure 1). In this review, we discuss the application of zebrafish as models in the pharmacology of AD, ...