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16 天
IL-2 家族信号途径及功能|茁彩生物
以下是对IL-2家族受体、配体成员的详细总结: 这些细胞因子通过激活不同的信号通路(如JAK-STAT、PI3K-AKT、MAPK等)来发挥其细胞学功能。 它们各自在免疫系统中扮演不同角色,如IL-2促进T细胞和NK细胞的功能,IL-4支持Th2细胞发育,IL-7对T细胞发育至关重要 ...
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1 个月
JAK抑制剂:能否成为系统性红斑狼疮治疗的突破点?临床医生来看 ...
JAK抑制剂(JAKi)作为一种新型口服靶向治疗药物,为SLE的治疗带来了新希望。本文旨在总结来自临床试验和病例报告中有关JAKi在SLE中的现有数据 ...
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