A new approach to targeting a protein involved in cell division, which can misfunction in cancer, has revealed new insights ...

Arrowhead Pharmaceuticals, Inc. (NASDAQ: ARWR) today announced that it has filed a request for regulatory clearance to initiate a Phase 1/2a clinical trial of ARO-ALK7, the company’s second ...

In Singapore, the local incidence of alopecia areata is 3.8%. The Health Sciences Authority has approved LITFULO ...

Signal binding to membrane receptor tyrosine kinases (RTKs) activates an enzyme called a kinase. Learn how kinases initiate a signaling cascade that relays information to the nucleus.

SELLAS Life Sciences Group has announced positive data from preclinical studies identifying the ASXL1 mutation as a ...

XOMA Royalty Corp. (XOMA), a biotechnology royalty aggregator, Monday announced that it now owns royalty and milestone interest in ...

WNKs sense osmotic pressure by binding specific water molecules to the inactive dimeric configuration of WNK1 and WNK3, integrating signals with chloride inhibition as demonstrated by mutagenesis and ...

Novel macrocyclic heteroaryl derivatives acting as non-receptor tyrosine-protein kinase TYK2 and/or JAK1 and/or JAK2 inhibitors have been reported in a Hangzhou Highlightll Pharmaceutical Co. Ltd.

but it is always difficult to relate inhibitor occupancy to phenotype.” Putting a drug, for example, a kinase inhibitor, on cells and measuring the effect gives researchers important insights ...

With over 15 years of experience in kinase drug discovery, DiscoverX offers the largest collection of nearly 500 biochemical and cell-based kinase assays. KINOMEscan® technology, our novel kinase ...

Physical exercise or strenuous sporting activities can increase blood creatine kinase (CK) levels—something to bear in mind in patients with suspected statin-associated muscle symptoms.

Background: The serum concentration of creatine kinase (CK) is used widely as an index of skeletal muscle fibre damage in sport and exercise. Since athletes have higher CK values than non-athletes, ...