Development of B cells, white blood cells that make antibodies, follows a progression of stages: common lymphoid progenitors, ...

Development of B cells, white blood cells that make antibodies, follows a progression of stages: common lymphoid progenitors, pre-pro-B cells, pro-B ...

Discover important insights into the clonal evolution of blastic plasmacytoid dendritic cell neoplasm, a rare and aggressive ...

Immunity plays a central role in the fight against cancer. Many of the current immunotherapies aim at helping the patient's immune system to better ...

Immunity plays a central role in the fight against cancer. Many of the current immunotherapies aim at helping the patient's ...

This new experimental platform showed a superior ability to produce and sustain a balanced immune cell population, accurately ...

Lymphoid tissues are organized structures that support immune responses. The bone marrow and thymus are primary lymphoid tissues and the sites of lymphocyte development. The lymph nodes ...

Innate lymphoid cells (ILCs) are immune cells that belong to the lymphoid lineage but do not express antigen-specific receptors. These cells have important functions in innate immune responses to ...

Following a comprehensive multidisciplinary consultation, the patient underwent an anatomical hepatectomy. Histopathological examination post-surgery confirmed the diagnosis of primary hepatic ...

Concurrent with ADI-001 tissue trafficking and activation, complete depletion of CD19+ B cells within analyzed secondary lymphoid tissue was also observed. These results support ADI-001’s ...

Additionally, the spatial organization of immune cells within the tumor microenvironment can be of major importance. For example, the presence of highly organized ectopic lymphoid structures, called ...

However, recent studies by Rodrigues et al. (Nature Immunology, 2018) and Dress et al. (Nature Immunology, 2019) have challenged this perspective, proposing that pDCs predominantly develop from ...