B and T cells develop in the bone marrow and thymus, respectively, from lymphoid progenitors, which arise from haematopoietic stem cells (HSCs) in the bone marrow. It is known that Notch ...

Further work 6 showed that the treatment of lymphoid progenitor cells with IL-3 resulted in the phosphorylation of BAD at two sites, serine residues 112 and 136 (this numbering is based on the ...

Bone marrow contains a heterogeneous mixture of mature and maturing precursors of blood cells, progenitor cells for myeloid and lymphoid lineages, and hematopoietic and mesenchymal stem cells.

Fibroblastic reticular cells (FRCs) create T-cell-supportive niches within lung cancer tumors, facilitating T-cell migration, ...