Results The GCPM ecosystem coordinates a unique immunosuppressive pattern distinct from that of primary GC, which is dominated by a stroma-myeloid niche composed of SPP1+tumour-associated macrophages ...

SCARF1 is a scavenger membrane-bound receptor that binds modified versions of lipoproteins and has a significant role in maintaining lipid homeostasis. This useful study reports the crystal structure ...

The biotechs teamed up to develop a method to engineer immune cells called macrophages to target solid tumors. Weekly dosing of the therapy, dubbed CAR-M, shrank lung and liver tumors in mice ...