The biotech’s approach to fighting cancer is based around “repolarising” tumour-associated macrophages (TAMs) using small molecule drugs so that they no longer suppress the immune system ...
Enlivex Therapeutics Ltd. (Nasdaq: ENLV, the “Company”), a clinical-stage macrophage reprogramming immunotherapy company, today announced positive interim efficacy data from the Phase I stage of its ...
A stroma-myeloid niche composited of SPP1+tumour-associated macrophages and THBS2+matrix cancer-associated fibroblasts (mCAFs ... This study was approved by the Ethics Committee of Sun Yat-sen ...
Results Overall, 252 macrophage-associated myelin lesions were identified in longitudinal sections. Of these, 40 lesions exhibited complete demyelination with no association with the lamellar ...
further supporting that FABP4-mediated lipolysis in macrophages was critical for lipid utilization by breast cancer cells. TAMs are the most abundant immune cells in breast cancer. To interrogate ...