As Rare Disease Day is commemorated on 28 February, experts discuss the barriers to gene therapy access for some rare ...

RNA-based therapeutics have rapidly emerged over the past decade, offering a new class of medicines that differ significantly from conventional drugs. These therapies can be programmed to target or ...

Artificial sweeteners, specifically aspartame, are under scrutiny following a WHO classification as 'possibly carcinogenic to ...

It is a good idea to leave them unpruned over winter: they provide food and shelter for wildlife and can look attractive even in decay, particularly when sprinkled with frost on cold mornings ...

D,L-phenylalanine and D-L-dihydroxyphenyalanine ... and this could have reduced DOPA available for brain metabolism. Chlorpromazine has also been reported to increase skin pigmentation 26 as ...

Only one sequence specificity rule is known for γ-secretase substrate processing: Aromatic residues such as phenylalanine are not tolerated in the P2′ position with respect to any processing event on ...

Natural ways to boost metabolism can be fun and easy. Simple things like eating more protein, high-intensity interval training, lifting weights, avoiding skipping meals, drinking the right things, ...

Tetralogy of Fallot (TOF) is a combination of four congenital (present at birth) heart defects that affect infants and children. The defects occur together and change the way blood flows through the ...

Objectives To investigate the effect of the L-arginine metabolism on arthritis and inflammation-mediated bone loss. Methods L-arginine was applied to three arthritis models (collagen-induced arthritis ...

Results: After DHI treatment, cardiac morphology and function as well as the metabolism in model rats were improved. We identified 17 differential metabolites and six metabolic pathways. Two ...